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Study begin: 1st. October 2015 Study end: 1st. October 2016
Locations: Cardiology Charité-Mitte, Cardiology and BIH-CRU Campus Benjamin Franklin, german Heart Centre and Cardiology Campus Virchow-Klinikum.
Financing: Gender in Medicine (GiM) and Foundation
Project leadership: Prof. Dr.med. Dr.h.c. Vera Regitz-Zagrosek
Cooperation partners: Prof. Dr.med. Christine Heim, Prof. Dr.med. Ulf Landmessser, Prof. Dr.med. Verena Stangl, Prof. Dr.med. Volkmar Falk, Prof. Dr.med. Jeanette Schulz-Menger, Prof. Dr.med. Burkert Pieske
Study doctor: Dr. med. Ute Seeland
Takotsubo cardiomyopathy (stress cardiomyopathy) is an acute coronary syndrome with typical local contraction weakness of the heart muscle, usually at the apex of the heart. This heart failure is very often triggered by severe mental stress situations and affects > 90% postmenopausal women. Takotsubo cardiomyopathy is a life-threatening disease with an 8% mortality. The causes are not fully understood yet. There is no specific therapy and an individual prognosis is not possible.
Course of the study
In this study, we examined cardiovascular health of women and men with Takotsubo cardiomyopathy and compared the results of the study with controls in whom this cardiac event did not occur. In addition to surveying stress events and current living conditions, we performed blood pressure and vascular stiffness examinations. In addition to the measurement of weight, size and waist circumference, an ECG diagnosis was performed. For the cardiac risk factors and pre-existing diseases, the respondents answered a detailed questionnaire.