Dr. Maria-Luisa Barcena de Arellano

Researcher, Leitung Nachwuchsgruppe

Charité – Universitätsmedizin Berlin
Hessische Str. 3-4
10115 Berlin

Campus / internal address:
Hessische Str. 3-4

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Research interests

  • Study of sex differences in chronic inflammatory diseases
  • Effects of Oestrogen in immnunmodulation in cardiovascular diseases
  • Study of sex differences in immune cell/fibroblast interaction in vitro and in vivo
  • Neuroimmunmodulation in chronic inflammatory diseases

Models and Techniques

Microsurgery models for myocardial hypertrophy (transverse aortic constriction (TAC) and myocardial infarction (MI), echocardiography, transgenic/knock in/knock out mice, behavioral experiments, pain paradigms, flow cytometry, Isolation and culturing of monocyte and macrophages (human, mouse, rat), cloning, confocal microscopy, IHC, molecular biological techniques


"Role of Sirt3 in the anti-inflammatory effects of estrogen receptors (ER) signaling"; PI, DZHK B 15-029 Extern (Céline Christiansen, master student) "Sex differences in oestrogen-dependent immune responses in experimental autoimmune myocarditis" (Maximilian Niehues, medical student) Role of Sirt1 in the anti-inflammatory effects of estrogen receptors signaling (Daniel Pannwitz, master student) "Sex-differences in the regulation of micro RNAs in chronic myocarditis"

Additional information

Selected Publications:

Barcena de Arellano ML, Oldeweme J, Arnold J, Schneider A, Mechsner S. (2013). "Remodeling of estrogen-dependent sympathetic nerve fibers seems to be disturbed in adenomyosis" Fertil Steril 100 (3): 801-809e2.
Otte DM, Barcena de Arellano ML, Bilkei-Gorzo A, Albayram O, Imbeault S, Jeung H, Alferink J, Zimmer A. (2013).

"Effects of chronic D-serine elevation on animal models of depression and anxiety-related behaviour". PLoS One 8 (6): e67131.
Arnold J, Vercellino GF, Chiantera V, Schneider A, Mechsner S, Barcena de Arellano ML. (2013).

"Neuroimmunomodulatory alterations in non-lesional peritoneum close to peritoneal endometriosis". NIM 20 (1): 9-18.

Arnold J, Barcena de Arellano ML, Rüster C, Vercellino GF, Chiantera V, Schneider A, Mechsner S. (2012). "Dysbalance of the sympathetic and sensory innervation in peritoneal endometriosis". Brain Behav Immu 26 (1): 132-41.

Barcena de Arellano ML, Arnold J, Vercellino GF, Chiantera V, Schneider A, Mechsner S. (2011). "Overexpression

Vita Dr. Maria-Luisa Barcena de Arellano

Here you can download the CV as a PDF.

Functions / offices

Since 2009 | Bachelor, master and PhD Supervisor

Since 2011 | Teaching, CharitéUniversitätsmedizin Berlin

Since 2015 | Breeding coordinator, Institute for Gender in Medicine, CharitéUniversitätsmedizin Berlin